Patterns of Resting Cerebral Blood Flow in Autism Spectrum Disorder Associated with Sensory-Motor Dysfunction, ADHD, and Autistic Features
DOI:
https://doi.org/10.64229/ckvhte68Keywords:
Cerebral Blood Flow (rCBF), Autism Spectrum Disorders (ASD), Sensory-Motor IntegrationAbstract
Neurological soft symptoms, motor difficulties, hyperactivity, and inattention characterize autism spectrum illnesses. These symptoms are linked to patterns of regional cerebral blood flow (rCBF) during rest. Nonetheless, the links are not obvious. A PET scanner was utilized to study 133 patients with ASD and 10 healthy controls with properly developing brains. In a factorial experiment, regional cerebral blood flow (rCBF) was shown to connect with autism, attention deficit hyperactivity disorder (ADHD), and neurological soft symptoms. We looked at the parameters linked with "autistic/ADHD characteristics," "sensory-motor integration," and "cognitive/motor sequencing" separately. Brain regions associated with "autistic/ADHD traits" (in the bilateral caudate and inferior parietal lobule), "sensory-motor integration" (in the parieto-occipital cortex), and "intelligence/motor sequencing" (in the right temporal lobe) have a positive correlation with cerebral blood flow in people with ASD. All three parameters negatively correlated blood flow to the left thalamus and cerebral cortex. Autism and attention deficit hyperactivity disorder (ADHD) have underlying brain connections. The link between "autistic/ADHD traits" and regional cerebral blood flow in the caudate nucleus might explain the executive dysfunctions and repetitive or stereotyped behaviors seen in ASD. A song's relationship with the aberrant visual perception seen in Autism Spectrum Disorder (ASD) connects the occipital visual cortex to sensory-motor problems and regional cerebral blood flow. Autism spectrum disorder (ASD) is thought to be characterized by a convergence of behavioral and neurological features.
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